Not sure if this is really considered a tweak or useful but I love it and everyone i show it to does also. Works on 98se to XP.
Create a new folder of any name in my Documents, now put any shortcut to a program you would like. Drag the folder drom the DOCument folder onto your task bar where your clock is. Now you have a customized quick folder for accessing programs on the fly without the clutter of desktop icons.
Hope you like =)