As soon as you install Windows Vista you are bombarded by the Welcome Center that is designed to help beginner Windows users easily configure their new computer.  This new welcome screen is a nice feature the first time you start using Windows vista but quickly becomes annoying. 

Disabling the Welcome Center is very easy to do and can speed up your boot as well. 

1. Start Regedit.

2. Navigate through HKEY_CURRENT_USER, Software, Microsoft, Windows, CurrentVersion, Run.

3. Right click on the WindowsWelcomeCenter key and select Delete.

The next time you restart the Welcome Center will be gone.